The Working Group on Antifungal Epidemiological Cutoff Values is requesting submission of raw antifungal susceptibility testing data for yeasts and filamentous fungi using the protocols provided in the most current editions of CLSI documents M27, Reference Method for Broth Dilution Antifungal Susceptibility Testing of Yeasts and M38, Reference Method for Broth Dilution Antifungal Susceptibility Testing of Filamentous Fungi. This request is only for reference broth microdilution and should not include data generated using commercially available panels. Because the data will be combined with data from other laboratories, even a small amount of data is useful, especially for the more infrequently identified species. All species should be identified using a molecular assay or matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.
Please submit data using the Antifungal Data Submission Sheet. (Clicking the link displays options to open or save the .zip file. Users must save the file before opening.) Instructions are provided below. Submit completed worksheets to CLSI at firstname.lastname@example.org.
Quality Control Instructions*
If QC data are not available from the time period when patient isolates were tested, include recent data and a comment explaining whether or not there have been any significant shifts in QC results. A QC data sheet is included for Candida isolates C. parapsilosis ATCC®† 22019 and C. krusei ATCC® 6258. If other isolates were used, please change the name on the sheet.
* In order to ensure QC of all results, CLSI requests your QC results for the time of testing.
† ATCC® is a registered trademark of the American Type Culture Collection.