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C64: Quantitative Measurement of Proteins and Peptides by Mass Spectrometry

CLSI requests nominations for volunteers to serve as members and contributors on a document development committee for a new document.

Description

CLSI document C64 will provide information on theoretical and practical descriptions of the steps for developing a method for quantitative measurement of proteins and peptides by mass spectrometry, from inception through validation. The guideline will include broad comparisons to currently accepted practices for quantitative analysis of small molecules with concentration on specific areas unique to proteins and peptides. The guideline will not focus on tutorials or instructions for the use of specific protein informatics software tools.

This group is looking for volunteers with:

  • Expertise in:
    • Chromatography (high-performance liquid chromatography, capillary electrophoresis)
    • Protein chemistry
    • Basic protein informatics
    • Quantitative peptide and protein measurement by mass spectrometry
    • Metrological processes and systems 
  • Experience in:
    • Assay development
    • Validation in a regulated medical laboratory environment

Additional information on essential job duties and skills and abilities for CLSI committee participants can be viewed here.

Timeline for this project

October 2017 to February 2018: Monthly conference calls 
Week of March 18, 2018: First face-to-face meeting (NOTE: This will be a 2-day meeting scheduled during the March Committees Week in Baltimore, Maryland.) 
April 2018 to November 2018: Drafting of document (higher-intensity volunteer time period)
January 2019 to March 2019: Voting period for draft document
April 2019 to May 2019: Revision of draft based on comments received during voting
August 2019: Expected publication date

Due date for submission of required documentation

Please submit nominations and required documentation (see Requirements for Nomination Consideration) on or before August 28, 2017 to volunteer@clsi.org.