Join us in celebrating our 50th Anniversary!
Join us in celebrating our 50th Anniversary!

M53: Criteria for Testing and Diagnosis of Human Immunodeficiency Virus Infection, 2nd Edition

CLSI requests nominations for volunteers to serve as members and contributors on a document development committee for a document revision.


CLSI document M53 will provide an overview of the natural history of and response to human immunodeficiency virus (HIV) infection, an in-depth review of initial and supplemental tests for the diagnosis of HIV infection, and initiation of a quality control program for HIV testing. This guideline will also cover special situations that commonly confound HIV testing, including the diagnosis of acute and recent HIV infection; initial and supplemental testing during pregnancy, labor, and delivery; and newborn testing. Special attention will also be given to testing for HIV-1, non-B subtype, and HIV-2 infection. Diagnostic testing algorithms will be provided to assist clinicians and laboratorians in the stepwise use of these tests, as well as a framework for additional testing and results interpretation. Furthermore, reporting criteria for commonly obtained test results will be provided.

This group is looking for volunteers with:

  • Experience in and knowledge about the design and development of HIV tests for clinical and industrial applications
  • Experience in and knowledge about the validation and verification of HIV tests for clinical and industrial applications
  • Technical expertise in the molecular and diagnostic detection of HIV
  • Experience in and knowledge about the interpretation and reporting of HIV test results

Additional information on essential job duties and skills and abilities for CLSI committee participants can be viewed here.

Timeline for this project

Week of May 31 to June 5, 2018: First face-to-face meeting (NOTE: This will be a 2-day meeting scheduled during the June Committees Week in San Diego, California.)
June 2018 to May 2019: Drafting of document (higher-intensity volunteer time period)
August 2019 to October 2019: Voting period for draft document
November 2019 to March 2020: Revision of draft based on comments received during voting
December 2020: Expected publication date

Due date for submission of required documentation

Please submit nominations and required documentation (see Requirements for Nomination Consideration) on or before March 15, 2018 to