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VET09: Understanding Susceptibility Test Data as a Component of Antimicrobial Stewardship in Veterinary Settings

CLSI requests nominations for volunteers to serve as members and contributors on a document development committee for a new document.


CLSI document VET09 will explain and provide examples of the optimal use of antimicrobial susceptibility testing (AST) results to support antimicrobial therapy decision making and good antimicrobial stewardship. This report will offer perspective to laboratories and veterinary clinicians on understanding and applying AST results that are generated using CLSI standard methods (CLSI document VET01) and interpreted using veterinary-specific breakpoints approved by the CLSI Subcommittee on Veterinary Antimicrobial Susceptibility Testing (VAST). Additionally, VET09 will fill knowledge gaps currently limiting the most effective use of AST laboratory results. In veterinary medicine, breakpoints and interpretive categories for some animal species, pathogens, antimicrobial agents, or infection sites are often unavailable. This report will provide available evidence for the applicability of veterinary-specific breakpoints and interpretive categories to animal species, bacterial pathogens, infection sites, or other antimicrobial agents of similar class that do not have approved breakpoints. Finally, VET09 will provide users with the Subcommittee on VAST’s current understanding of limitations when interpreting AST results for isolates not explicitly listed in CLSI standards.

This group is looking for volunteers with:

  • Expertise in veterinary clinical microbiology
  • Expertise in veterinary clinical pharmacology
  • Experience in clinical management of bacterial infections in various animal species
  • Familiarity with antimicrobial stewardship principles and knowledge of judicious antibiotic use
  • General knowledge of CLSI processes
  • Familiarity with CLSI Subcommittee on VAST breakpoint-setting processes for antimicrobial agents used to treat animals
  • Knowledge of regulatory aspects of antimicrobial selection and use in animals

Additional information on essential job duties and skills and abilities for CLSI committee participants can be viewed here.

Timeline for this project

January 27-28, 2018: First face-to-face meeting (NOTE: This will be a 2-day meeting scheduled during the January 2018 Committees Week in Dallas, Texas.)
October 2017 to July 2018: Drafting of document (higher-intensity volunteer time period) 
July 2018 to August 2018: Voting period for draft document
September 2018 to October 2018: Revision of draft based on comments received during voting
February 2019: Expected publication date

Due date for submission of required documentation

Please submit nominations and required documentation (see Requirements for Nomination Consideration) on or before August 24, 2017 to volunteer@clsi.org.