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CLSI Blog Articles

Read the latest articles about CLSI and laboratory standards in the official CLSI Blog. Browse our most recent blog articles below.

AST News Update June 2022: Updating Breakpoints–New Developments from CAP

The College of American Pathologists (CAP) is introducing two new requirements for clinical laboratories to use updated breakpoints (BPs) when interpreting antimicrobial susceptibility testing (AST) results. CAP has recognized that some laboratories are using obsolete breakpoints, even when devices have achieved US Food and Drug Administration (FDA) clearance for updates, which could lead to adverse consequences in managing patients.

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candida

AST News Update June 2022: Hot Topic

Candida auris is an emerging yeast that is causing numerous outbreaks in health care settings, and life-threatening infections in patients worldwide.1 Most isolates of C. auris are multidrug resistant.

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Monkeypox Testing Guidance and Resources

The US Centers for Disease Control and Prevention (CDC) is tracking multiple cases of monkeypox that have been reported in several countries that don’t normally report monkeypox, including the United States. They are urging healthcare providers in the US to be alert for patients who have rash illnesses consistent with monkeypox and are working with state and local health officials to identify people who may have been in contact with individuals who have tested positive for monkeypox, so they can monitor their health. According to CDC, Monkeypox is rare and does not spread easily between people without close contact. The threat of monkeypox to the general US population remains low.

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Glen Fine, Chief Executive Officer, CLSI

CEO Glen Fine's Farewell Message

As I depart CLSI and enter the new phase of retired life, I would like to take a moment to reflect and give my thanks to all who have made my 17 years as your CEO the most rewarding and deepest honor of my life.

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FeaturedArticle_062022

Implementation of the CLSI Method for Direct Disk Diffusion Testing From Positive Blood Cultures

The CLSI AST Subcommittee has developed and published breakpoints for direct blood culture disk diffusion (DD) testing of several antimicrobial agents for Enterobacterales and Pseudomonas aeruginosa. This project was undertaken to provide antimicrobial susceptibility testing (AST) results earlier than traditional AST methods. Rapidity of susceptibility testing and reporting is particularly important for bloodstream infections. Studies have shown that mortality from sepsis increases every hour that the time to first appropriate antimicrobial is delayed. CLSI developed this method to provide laboratories with a direct-from-blood culture testing approach which is both simple to perform and inexpensive.

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CLSI’s June 2022 AST Committees Week Meetings

CLSI’s June 2022 AST Committees Week Meetings will be held 25-28 June at Loews Chicago O’Hare Hotel. There will be nine in-person meetings. Virtual pre-meetings of the Methods Development and Standardization Working Group and Quality Control Working Group are scheduled on Wednesday, 15 June 2022. For the first time, CLSI will be hosting the AST Committees Week Meetings in hybrid format, to accommodate attendees who prefer to participate virtually.

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Dr. Harry Hannon’s Passing

We are deeply saddened to announce the death of long-time CLSI volunteer William Harry Hannon, PhD. For most of his long career, Dr. Hannon was known for his leadership in developing and supporting public health laboratory newborn screening using dried blood spots, preventing infant death, and enhancing the lives of children and families both here in the US and around the globe.

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