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CLSI standards and guidelines are developed for use by the global laboratory community. Purchase clinical laboratory standards documents from our shop.

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CLSI's collaborative approach ensures balanced representation from the global laboratory community to yield unbiased consensus standards for global use.

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Through our Partnerships program, CLSI provides international outreach services and hands-on support to laboratories in resource-constrained countries, helping them achieve sustainable quality with systems to better diagnose and treat patients with infectious diseases.

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The Clinical & Laboratory Standards Institute (CLSI) is a not-for-profit membership organization dedicated to fostering excellence in laboratory medicine.

CLSI Susceptibility Testing Subcommittees and Resources

Advancing the Field of Microbiology with Timely AST Standards

Find the latest news and updates from our microbiology standards committees.

Why Use CLSI Breakpoints?       Free Resources       AST Rationale Documents       AST Subcommittee E-mail List

About the Susceptibility Testing Subcommittees

Subcommittees are responsible for two or more related documents in a topic area. They write draft documents, evaluate and respond to comments on content throughout the document development process, conduct scheduled document reviews, and may be responsible for continual revision of certain documents.

CLSI has established subcommittees in the following areas:

Antimicrobial Susceptibility Testing (AST) Subcommittee

The AST Subcommittee provides useful information to laboratories, enabling them to advise clinicians in the selection of appropriate antimicrobial therapy.

More About AST

Antifungal Susceptibility Testing Subcommittee

The Antifungal Subcommittee collaborates to develop standards and guidelines that promote accurate antifungal susceptibility testing and appropriate reporting.

More About Antifungal

Veterinary Antimicrobial Susceptibility Testing (VAST)

The VAST Subcommittee collaborates to develop standards and guidelines that promote accurate antimicrobial susceptibility testing and appropriate reporting.

More About VAST

Susceptibility Testing Resources

Access Our Free Microbiology Standards Resources

M100 and M60 Free

Performance Standards for Antimicrobial Susceptibility Testing, 30th Edition

This document includes updated tables for the Clinical and Laboratory Standards Institute antimicrobial susceptibility testing standards M02, M07, and M11.

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AST Rationale Documents (Free)

Product MRPKG

Providing the scientific reasons behind breakpoint decisions.

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M23

Development of In Vitro Susceptibility Testing Criteria and Quality Control Parameters, 5th Edition

This guideline discusses the necessary and recommended data for selecting appropriate breakpoints and quality control ranges for antimicrobial agents.

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VET01S Free

Performance Standards for Antimicrobial Disk and Dilution Susceptibility Tests for Bacteria Isolated From Animals, 5th Edition

This document includes updated tables for the Clinical and Laboratory Standards Institute veterinary antimicrobial susceptibility testing standard VET01.

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Volunteering With CLSI

Hear directly from our volunteers about their experience volunteering on CLSI AST Subcommittees.

Meetings

Future Meetings

January-February 2021
Virtual

June 2021
Virtual

Recent Meetings

August-October 2020
Virtual

January 23–26, 2020
Tempe, Arizona, USA

Staff Liaisons

AST and Antifungal Staff Liaison | Marcy L. Hackenbrack, MCM, M(ASCP)

VAST Staff Liaison | Lori T. Moon, MS, MT(ASCP)

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On-Demand CLSI and CAP 2021 Webinar

Ensuring Quality Beyond the Test: Reporting Antimicrobial Susceptibility Results

Thursday, January 21, 2021 | 1:00–2:00 PM Eastern (US) Time

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M59

Epidemiological Cutoff Values for Antifungal Susceptibility Testing, 3rd Edition

This document provides epidemiological cutoff values developed according to the criteria in the Clinical and Laboratory Standards Institute (CLSI) guideline M57 and generated according to the reference broth dilution methods described in the CLSI standards M27 and M38.

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M60

Performance Standards for Antifungal Susceptibility Testing of Yeasts, 2nd Edition

This document provides updated minimal inhibitory concentration, zone diameter, and quality control tables for the Clinical and Laboratory Standards Institute antifungal susceptibility testing documents M27 and M44.

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M61

Performance Standards for Antifungal Susceptibility Testing of Filamentous Fungi, 2nd Edition

This document provides minimal inhibitory concentration breakpoints and quality control tables for the Clinical and Laboratory Standards Institute antifungal susceptibility testing documents M38 and M51.

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