CLSI H59 Volunteer Application

CLSI H59 | Quantitative D-dimer for the Exclusion of Venous Thromboembolic Disease, 2nd Edition

CLSI H59 will provide information on proper specimen collection and handling for D-dimer testing, the value of clinical determination for the pretest probability of venous thromboembolism, establishment of the threshold for exclusion of venous thromboembolism, types of assays used for D-dimer analysis, interpretation of test results, as well as regulatory and accreditation considerations for D-dimer testing.

This group is looking for volunteers with:

• Expertise performing D-dimer assays

• Experience establishing thresholds and interpreting D-dimer results for the exclusion of venous thromboembolic disease

• Experience in validating coagulation assays

• Expertise in the collection, handling, preparation, and storage of coagulation specimens

• Experience in the manufacturing process for coagulation analyzers and assay

Estimated Timeline 

• May 2026: First meeting (may include review of document scope and outline, assignment of writing teams)
• May 2026 to January 2027: Drafting of document (higher-intensity volunteer time period)
• June 2027 to July 2027: Voting period for draft document
• July 2027 to September 2027: Revision of draft based on comments received during voting
• February 2028: Expected Final Draft approval date

Apply on or before 27 March 2026.