Standard Document
Second Edition
Quality Management Systems

CLSI GP20

Fine Needle Aspiration Biopsy (FNAB) Techniques

This document provides recommended procedures for performing fine needle aspiration biopsies of both superficial (papable) and deep-seated (nonpalpable) lesions, from patient preparation to staining the smear.

 

October 20, 2003
Nina Dhurandhar, MD

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Abstract

Clinical and Laboratory Standards Institute document GP20-A2—Fine Needle Aspiration Biopsy (FNAB) Techniques; Approved Guideline—Second Edition describes procedures for collecting, handling, fixing, and staining aspiration biopsy specimens. Equipment and aspects of patient preparation necessary to obtain a fine needle biopsy specimens are also addressed. Interpretation of smears is not included in this guideline.

Scope

Fine needle aspiration biopsy is a widely accepted technique for the initial work-up and management of a patient who presents with a superficial, palpable lesion/mass. This technique is also used for a deep-seated, nonpalpable lesion/mass under radiologic guidance. This minimally invasive procedure is safe, accurate, rapid, and cost effective. Patient acceptance is high and complications are minimal. The goal of this guideline is to provide recommendations for performing the procedure and optimal collection, handling, fixation, and staining of aspiration biopsy specimens. Equipment needs and patient preparation issues are addressed. NCCLS document GP20-A2 is not, however, intended to summarize the morphologic features used for diagnosis.

Product Details
GP20A2E
1-56238-509-7
48
Additional Details

The U.S. Food and Drug Administration (FDA) has evaluated and recognized this approved-level consensus standard for use in satisfying a regulatory requirement.

This document is available in electronic format only.

This archived document is no longer being reviewed through the CLSI Consensus Document Development Process. However, this document is technically valid and because of its value to the laboratory community, it is being retained in CLSI’s library.

Authors
Nina Dhurandhar, M.D., Chairholder
Harvey Cramer, M.D.
Leza N. Gallo, M.D.
Daniel F.I. Kurtycz, M.D.
Krzysztof Moroz, M.D.
Margaret H. Neal, M.D.
Marianne Prey, M.D.
Gail Radcliffe, Ph.D.
Suzanne M. Selvaggi, M.D.
Abstract

Clinical and Laboratory Standards Institute document GP20-A2—Fine Needle Aspiration Biopsy (FNAB) Techniques; Approved Guideline—Second Edition describes procedures for collecting, handling, fixing, and staining aspiration biopsy specimens. Equipment and aspects of patient preparation necessary to obtain a fine needle biopsy specimens are also addressed. Interpretation of smears is not included in this guideline.

Scope

Fine needle aspiration biopsy is a widely accepted technique for the initial work-up and management of a patient who presents with a superficial, palpable lesion/mass. This technique is also used for a deep-seated, nonpalpable lesion/mass under radiologic guidance. This minimally invasive procedure is safe, accurate, rapid, and cost effective. Patient acceptance is high and complications are minimal. The goal of this guideline is to provide recommendations for performing the procedure and optimal collection, handling, fixation, and staining of aspiration biopsy specimens. Equipment needs and patient preparation issues are addressed. NCCLS document GP20-A2 is not, however, intended to summarize the morphologic features used for diagnosis.

Additional Details

The U.S. Food and Drug Administration (FDA) has evaluated and recognized this approved-level consensus standard for use in satisfying a regulatory requirement.

This document is available in electronic format only.

This archived document is no longer being reviewed through the CLSI Consensus Document Development Process. However, this document is technically valid and because of its value to the laboratory community, it is being retained in CLSI’s library.

Authors
Nina Dhurandhar, M.D., Chairholder
Harvey Cramer, M.D.
Leza N. Gallo, M.D.
Daniel F.I. Kurtycz, M.D.
Krzysztof Moroz, M.D.
Margaret H. Neal, M.D.
Marianne Prey, M.D.
Gail Radcliffe, Ph.D.
Suzanne M. Selvaggi, M.D.