CLSI has a longstanding globally trusted reputation for its diligent development of Microbiology and Antimicrobial Susceptibility Testing (AST) standards and guidelines on test methods and QC procedures. Additionally, CLSI annually creates and revises AST breakpoints to meet global public health challenges related to antimicrobial resistance. CLSI’s library of Microbiology standards and AST guidelines establish vital performance criteria and best practice guidelines for use in the clinical microbiology laboratory field.
This rationale document is based on data compiled by the CLSI Ceftaroline Breakpoint Ad Hoc Working Group to support the changes to the ceftaroline minimal inhibitory concentration breakpoints for Staphylococcus aureus and introduce new resistant and susceptible-dose dependent breakpoints.
This document includes updated tables for the Clinical and Laboratory Standards Institute antimicrobial susceptibility testing standards M02, M07, and M11.
