CLSI M53

Criteria for Laboratory Testing and Diagnosis of Human Immunodeficiency Virus Infection, 2nd Edition

This guideline includes recommendations for performing human immunodeficiency virus testing and for interpretation of results by health care providers in advanced diagnostic laboratories.

This edition of the document was corrected in June 2024. Read the correction notice by accessing the link above, and learn more about our corrections process here.

This document is available in electronic format only.

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Chairholder: Eric S. Rosenberg, MD

Date of Publication: August 29, 2023

Order Code PDF: CLSI M53Ed2E
ISBN Number: 978-1-68440-188-8

Order Code Print: print not available

Edition: Second

Pages: 146

CLSI M53 Additional Details

A guideline for global application developed through the Clinical and Laboratory Standards Institute consensus process.

CLSI M53 Abstract

Clinical and Laboratory Standards Institute guideline M53—Criteria for Laboratory Testing and Diagnosis of Human Immunodeficiency Virus Infection provides an extensive review of existing laboratory methods commonly used to test for HIV infection. The accurate diagnosis of HIV infection is essential for limiting the spread of infection and for the appropriate clinical management of persons infected with HIV. Numerous tests and strategies have been developed and are used by laboratorians and clinicians to diagnose HIV infection. This guideline also offers recommendations for how to best use and interpret these tests accurately and effectively to diagnose HIV infection.