CLSI M58

Methods for the Identification of Cultured Microorganisms Using Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry, 1st Edition

This guideline includes performance, reporting, and quality assurance recommendations for the identification of cultured microorganisms by medical laboratory professionals using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Recommendations for end-user verification and workflow integration are also included.

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Chairholder: John A. Branda, MD

Date of Publication: April 26, 2017

Order Code PDF: CLSI M58Ed1E
ISBN Number: 1-56238-817-7

Order Code Print: CLSI M58Ed1
ISBN Number: 1-56238-816-9

Edition: First

Pages: 92

CLSI M58 Abstract

Clinical and Laboratory Standards Institute guideline M58—Methods for the Identification of Cultured Microorganisms Using Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry provides guidance to the end user for adopting matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) in the medical laboratory setting. Included are procedures and guidelines for preparing and analyzing cultured patient isolates, interpreting and reporting results, and troubleshooting. Best practices are described for ensuring quality and safety, and guidelines are provided for the initial introduction of MALDI-TOF MS into an existing laboratory, including method verification, training development and competence assessment programs, and operational considerations.

CLSI M58

Methods for the Identification of Cultured Microorganisms Using Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry, 1st Edition

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CLSI M58 Abstract