CLSI MM11

Molecular Methods for Bacterial Strain Typing, 1st Edition

This guideline examines the biology behind molecular strain typing and the process of characterizing and validating typing systems. The prevalent methods are described with particular attention to pulsed-field gel electrophoresis (PFGE) and multilocus sequence typing (MLST).

This document is available in electronic format only.

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Chairholder: Robert D. Arbeit, MD

Date of Publication: April 16, 2007

Order Code PDF: CLSI MM11AE
ISBN Number: 1-56238-634-4

Order Code Print: print not available

Edition: First

Pages: 84

CLSI MM11 Additional Details

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This archived document is no longer being reviewed through the CLSI Consensus Document Development Process. However, this document is technically valid as of January 2017. Because of its value to the laboratory community, it is being retained in CLSI’s library.

CLSI MM11 Abstract

Clinical and Laboratory Standards Institute document MM11-A—Molecular Methods for Bacterial Strain Typing; Approved Guideline examines the biology behind molecular strain typing and the process of characterizing and validating typing systems. The prevalent methods are described with particular attention to pulsed field gel electrophoresis (PFGE) and multilocus sequence typing (MLST). Specific issues in analyzing typing data derived from these methods are discussed. The guideline offers a general approach, suitable for use in the situations commonly encountered in clinical laboratories, for interpreting and reporting molecular typing results. For selected bacterial pathogens, the application of molecular typing systems and the insights derived are considered in detail.