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Understanding Susceptibility Test Data as a Component of Antimicrobial Stewardship in Veterinary Settings, 2nd Edition

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CLSI VET09

Understanding Susceptibility Test Data as a Component of Antimicrobial Stewardship in Veterinary Settings, 2nd Edition

CLSI VET09 provides veterinarians with the information needed to successfully acquire and interpret antimicrobial susceptibility testing (AST) results. It promotes common understanding between the veterinarian and the veterinary microbiology laboratory by providing example culture and susceptibility reports and animal species-specific guidance on applying breakpoints to interpret AST results.

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Details

Chairholder: Virginia R. Fajt, DVM, PhD, DACVCP

Date of Publication: February 26, 2024

Order Code PDF: CLSI VET09Ed2E
ISBN Number: 978-1-68440-217-5

Order Code Print: CLSI VET09Ed2
ISBN Number: 978-1-68440-216-8

Edition: Second

Pages: 186

CLSI VET09 Abstract

Clinical and Laboratory Standards Institute VET09—Understanding Susceptibility Test Data as a Component of Antimicrobial Stewardship in Veterinary Settings discusses antimicrobial susceptibility testing (AST), which provides important, clinically relevant information to the submitting veterinarian, provided the veterinarian understands how the testing is performed and how the results can be interpreted. CLSI VET09 includes background information on laboratory processes, including how AST is performed, why AST may not be performed, and how AST results are assessed by the laboratory. It also describes the reasons for varying degrees of confidence in applying breakpoints for interpreting AST results, which will inform veterinarians as they make decisions about the use of antimicrobial agents to treat bacterial disease in animals. CLSI VET09 reviews some of the factors that affect antimicrobial drug selection in animals, including principles of antimicrobial pharmacology, the effect of bacterial species identification on AST results interpretation, and the veterinarian’s role in ensuring AST results are accurate and useful. The example AST reports include callout boxes, highlighting important facets of AST reports to help the veterinarian apply the data. CLSI VET09 has separate chapters for animal species–specific guidance on interpreting AST data for dogs, cats, horses, cattle, pigs, fish, and poultry. It also includes a chapter on guidance and limitations on interpreting AST data for animal species for which there are no approved breakpoints, including sheep, goats, donkeys and mules, camelids, and exotic animals. Uniquely, CLSI VET09 provides evidence-based appraisals of confidence in the AST data reported by laboratories. This guidance can also be used by laboratories to select appropriate breakpoints for assigning interpretive categories and to help client veterinarians interpret their data. CLSI VET09 includes information on the most recent veterinary-specific breakpoints published in CLSI VET01S Tables 2A to 2M.

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