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Read the latest articles about CLSI and laboratory standards in the official CLSI Blog. Browse our most recent blog articles below.
Clinical and Laboratory Standards Institute (CLSI) was excited to participate in the Association for Diagnostics & Laboratory Medicine (ADLM) 2023 Annual Meeting and Expo (formerly AACC). A celebration of ADLM’s 75th anniversary, the conference brought together over 70K participants from clinical chemistry, diagnostics, lab management, and other laboratory science areas.
Read MoreA 45-year-old patient with acute myeloid leukemia (AML) received induction chemotherapy 2 weeks ago and currently has an absolute neutrophil count of <100 cells/μL. The patient had been on levofloxacin prophylaxis for his neutropenia, but developed a fever a week ago, at which point meropenem was started. All cultures and imaging were negative.
Read MoreMajor changes to the aminoglycoside (gentamicin, tobramycin, and amikacin) breakpoints were published in CLSI M100-Ed33.
Read MoreA 60-year-old female with a history of colon cancer presented to the Emergency Department with acute onset of abdominal pain. She had a recent proctocolectomy (removal of rectum and part of colon). Her temperature was normal, blood pressure was 136/70, and heart rate was 149 beats per minute.
Read MoreIn the July 2020 issue of this News Update, cefiderocol (trade name Fetroja®, manufactured by Shionogi) was discussed to include its projected use, requirements for testing, and more. Since that time, several new developments have occurred for cefiderocol testing.
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The end of the federal COVID-19 Public Health Emergency (PHE) on May 11, 2023 means that medical laboratories and device manufacturers will need to adjust their reporting requirements. During the PHE, the Department of Health and Human Services (HHS) had the authority to require lab tests for COVID-19 be reported to the Centers for Disease Control (CDC). This reporting requirement is no longer in effect.
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CLSI has renamed its free read-only microbiology portal and added new standards essential for susceptibility testing. CLSI is committed to making resources broadly available to users around the globe to help improve health care and save lives. These free standards provide critical information for improving the management of infectious diseases, reducing antimicrobial resistance, and saving lives worldwide.
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The Centers for Disease Control and Prevention (CDC) issued a Health Alert Network (HAN) Health Advisory on April 6 about two confirmed outbreaks of Marburg virus disease (MVD) in Equatorial Guinea and Tanzania. To date, no confirmed cases of MVD related to these outbreaks have been reported in the United States or other countries. The CDC Health Advisory summarizes their recommendations for case identification, testing, and clinical laboratory biosafety considerations in the United States.
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Candida auris is a type of yeast that has become a growing concern in recent years due to its ability to cause severe infections that are difficult to treat. C. auris was first identified in 2009 in Japan, but since then has spread to other countries and become a global health threat.
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The Centers for Disease Control and Prevention (CDC) has issued a health alert after observing a sharp increase in the number of cases of extensively drug-resistant (XDR) Shigella–a bacteria that causes shigellosis, a major form of inflammatory diarrhea. According to the CDC, the proportion of Shigella infections in the US that are resistant to all known antibiotic treatments rose from zero in 2015 to 0.4% in 2019, before leaping to 5% last year.
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