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 CLSI Publishes New Chemistry Document C34—Sweat Testing: Specimen Collection and Quantitative Chloride Analysis

2/13/2019

Wayne, Pennsylvania, USAThe Clinical and Laboratory Standards Institute has published C34—Sweat Testing: Specimen Collection and Quantitative Chloride Analysis. C34 describes methods for performing sweat testing for cystic fibrosis diagnosis. Sweat stimulation, collection, and quantitative measurement of sweat chloride are described, along with results evaluation and reporting, quality assurance, and method validation.

C34 contains helpful appendixes with information on:

  • Sweat collection on gauze or filter paper and chloride analysis using a digital chloridometer with individual titration vials.
  • Sweat collection into coiled tubing and chloride analysis using a digital chloridometer with individual titration vials.
  • Clinical indications for sweat testing.
  • Pilocarpine nitrate concentration.
  • Current density.
  • Reported diseases or conditions other than cystic fibrosis associated with an elevated sweat electrolyte concentration.  

 For more information about C34, contact Patrick McGinn at pmcginn@clsi.org or +1.484.588.5933.   

 

CLSI sets the standard for quality in medical laboratory testing. A not-for-profit membership organization, CLSI brings together the global laboratory community for the advancement of a common cause: to foster excellence in laboratory medicine.  

For nearly 50 years, our members, volunteers, and customers have made CLSI a respected, transformative leader in the development and implementation of medical laboratory testing standards. Through our unified efforts, we will continue to set and uphold the standards that drive quality test results, enhance patient care delivery, and improve health care around the world.  

By using CLSI standards, laboratorians can improve process quality, speed the development of standard operating procedures, and implement safer practices with greater ease and efficiency. 

 

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