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Global Standards for Antimicrobial Susceptibility Testing

Maximize Your Lab’s Effectiveness With the Latest Editions of CLSI M02, M07 & M100


New this year, we have revised standards guidance for disk diffusion (CLSI M02) and disk dilution (CLSI M07), as well as new breakpoint tables (CLSI M100).

Make sure your lab has the latest guidance in antimicrobial susceptibility testing, breakpoints, and quality control! Use of these documents is critical to ensuring accurate testing results and better patient outcomes. Purchase all three documents together to receive discounted package pricing! See below for more information.

CLSI M100

Performance Standards for Antimicrobial Susceptibility Testing, 34th Edition

CLSI M100 includes updated tables for the Clinical and Laboratory Standards Institute antimicrobial susceptibility testing standards CLSI M02, M07, and M11. 

CLSI M02

Performance Standards for Antimicrobial Disk Susceptibility Tests, 14th Edition

CLSI M02 covers the current recommended methods for disk susceptibility testing and criteria for quality control testing.

CLSI M07

Methods for Dilution Antimicrobial Susceptibility Tests for Bacteria That Grow Aerobically, 12th Edition

CLSI M07 covers reference methods for determining minimal inhibitory concentrations of aerobic bacteria by broth macrodilution, broth microdilution, and agar dilution.

Register Now for the AST Updates Webinar on April 17!

Identify the major changes found in the updated edition of CLSI’s M100 and learn to design a strategy for implementing new laboratory practices.

CLSI On-Demand: 2024 M100 Update Webinar

What’s New in the 2024 CLSI Standards for Antimicrobial Susceptibility Testing?

Date: April 17, 2024 | 1:00-2:30 PM ET

Moderator: Janet Hindler, MCLS, MT(ASCP), F(AAM)
Speakers: April M. Bobenchik, PhD, D(ABMM), MT(ASCP) Romney M. Humphries, PhD, D(ABMM)

Join CLSI for a webinar on the latest in Antimicrobial Susceptibility Testing (AST) with the release of the 34th edition of the CLSI M100 document. Receive the latest guidance for implementing new breakpoints and standards into your laboratory practices. Some of the major changes that will be discussed during the webinar include a significant reorganization of dosage recommendations, addition of sulbactam-durlobactam to breakpoints, a new Table 2A-2 for Salmonella and Shigella, and many more. A few substantive changes to the upcoming CLSI M02 and M07 will also be discussed.

 

 

 

 

Featured CLSI Products | Access Breakpoint Implementation Guidance

CLSI Breakpoint Implementation Toolkit

Breakpoint Implementation Toolkit

Together CLSI, Association of Public Health Laboratories (APHL), American Society for Microbiology (ASM), College of American Pathologists (CAP), and Centers for Disease Control and Prevention (CDC), have jointly developed this Breakpoint Implementation Toolkit (BIT) to assist clinical laboratories in updating minimal inhibitory concentration (MIC) breakpoints.

CLSI BIT Webinar

Get Current! Using the 2023 Breakpoint Implementation Toolkit to Update and Document AST Breakpoints

Clinical and Laboratory Standards Institute (CLSI), Association of Public Health Laboratories (APHL), American Society for Microbiology (ASM), College of American Pathologists (CAP), and Centers for Disease Control and Prevention (CDC), have jointly developed this Breakpoint Implementation Toolkit (BIT) to assist clinical laboratories in updating minimal inhibitory concentration (MIC) breakpoints.

 

 

Other Ways to Access CLSI M100 Ed34

eCLIPSE

Access CLSI's full library of standards—including CLSI M100—with eCLIPSE Ultimate Access, an enhanced, premium platform with advanced features to help you access standards quickly and easily. Included in some membership levels or purchased separately.

Access Now

M100 Plus

Get full online access to M100, M02, M07, and M11 with added functionality and fast, easy data searching in an electronic format. Plus, you’ll have the added benefit of quick access to related materials via an AST Resource Center.

Access Now

MicroFree

With this read-only web version of M100, you can now quickly reference the most trusted AST breakpoints from anywhere with an Internet connection. Available online as a convenient companion to our M100 document.

Access Now

 

 

2024 AST Packages | Bundle these latest editions and receive them at a discounted rate.

With important updates for all three documents, CLSI is offering discount package pricing for those that choose to bundle and save.

CLSI CLSI M02 + M100 Print

CLSI M02 + M100 Print

CLSI M02 + M100 - Print

CLSI CLSI M02 + M100 PDF

CLSI M02 + M100 PDF

CLSI M02 + M100 PDF

CLSI CLSI M07 + M100 Print

CLSI M07 + M100 Print

CLSI M07 + M100 Print

CLSI CLSI M07 + M100 PDF

CLSI M07 + M100 PDF

CLSI M07 + M100 PDF

CLSI CLSI M02 + M07+ M100 Print

CLSI M02 + M07+ M100 Print

CLSI M02 + M07+ M100 Print

CLSI CLSI M02 + M07+ M100 PDF

CLSI M02 + M07+ M100 PDF

CLSI M02 + M07+ M100 PDF

 

 

Save With a CLSI Membership


Consider becoming a CLSI member to save up to 70% on documents and educational products and gain access to the most up-to-date standards via eCLIPSE, our full online library.

 

 

The Go-To Source for AST Methods and Interpretive Criteria

CLSI has a longstanding reputation for its diligent development of microbiology and antimicrobial susceptibility testing (AST) standards and guidelines on test methods and QC procedures. CLSI annually creates and revises AST breakpoints to meet global public health challenges related to antimicrobial resistance. CLSI is proud to support one health and fighting antimicrobial resistance.