CLSI EP12IG serves as an implementation guide for medical laboratories to verify the performance of qualitative, binary output examinations (e.g., yes/no, positive/negative, target condition present/absent). It outlines minimum procedures for assessing imprecision, clinical performance, stability, and interferences, ensuring the accuracy and reliability of qualitative test results. For additional information on verifying performance of qualitative examinations, see CLSI document EP12.