Standard Document
Eighth Edition
Preexamination Processes

CLSI PRE02

Collection of Diagnostic Venous Blood Specimens

CLSI PRE02 provides procedures for the collection of diagnostic venous blood specimens, including line draws, blood culture collection, and venipuncture in children.

February 13, 2025
Judith Dixon, MS, BS MT, ASCP; Estelle Ninnmenn

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Abstract

Clinical and Laboratory Standards Institute PRE02—Collection of Diagnostic Venous Blood Specimens provides a descriptive, stepwise process and procedures reflecting the quality system essentials format for diagnostic venous blood specimen collection. Special considerations for collections from vascular access devices, blood culture collection, and collections in isolation environments are included, as well as how to handle emergency situations. An expanded appendix section provides helpful tips for collecting specimens from pediatric and other challenging patients.

Overview of Changes

CLSI PRE02-Ed8 replaces CLSI GP41-Ed7, published in 2017. Several changes were made in this edition, including: 
• Removing duplicate information (ie, that included in CLSI PRE011) 
• Harmonizing content with other CLSI preexamination documents 
• Updating references

Scope

CLSI PRE02 establishes criteria for venous blood specimen collection for medical laboratory testing. These procedures are intended as an appropriate model for adoption by all health care providers responsible for blood specimen collection in outpatient and inpatient settings.

Product Details
PRE02Ed8E
978-1-68440-271-7
82
Previously Titled

GP41Ed7 GP41Ed7E

Authors
Judith Dixon, MS, MT(ASCP), BS Estelle Ninnemann, MLS(ASCP), MBA Terri A. McElhattan, MHA, MLS, PBT(ASCP), CPI(ACA) Michael O’Bryan, MD, MHA Aurora Munoz Pedraza, MC EHDL George F. Souza, PBT(ASCP), BS Cherise Ens, MSc., MLT Valerie Joyner, MBA, MLT(ASCP) Charles E. Walker, MLT(ASCP)
Supporting Resources
CLSI PRE02QG
Collection of Diagnostic Venous Blood Specimens Quick Guide, 8th Edition
Companion
Preexamination Processes
Free
Abstract

Clinical and Laboratory Standards Institute PRE02—Collection of Diagnostic Venous Blood Specimens provides a descriptive, stepwise process and procedures reflecting the quality system essentials format for diagnostic venous blood specimen collection. Special considerations for collections from vascular access devices, blood culture collection, and collections in isolation environments are included, as well as how to handle emergency situations. An expanded appendix section provides helpful tips for collecting specimens from pediatric and other challenging patients.

Overview of Changes

CLSI PRE02-Ed8 replaces CLSI GP41-Ed7, published in 2017. Several changes were made in this edition, including: 
• Removing duplicate information (ie, that included in CLSI PRE011) 
• Harmonizing content with other CLSI preexamination documents 
• Updating references

Scope

CLSI PRE02 establishes criteria for venous blood specimen collection for medical laboratory testing. These procedures are intended as an appropriate model for adoption by all health care providers responsible for blood specimen collection in outpatient and inpatient settings.

PRE02Ed8E
978-1-68440-271-7
82
Previously Titled

GP41Ed7 GP41Ed7E

Authors
Judith Dixon, MS, MT(ASCP), BS Estelle Ninnemann, MLS(ASCP), MBA Terri A. McElhattan, MHA, MLS, PBT(ASCP), CPI(ACA) Michael O’Bryan, MD, MHA Aurora Munoz Pedraza, MC EHDL George F. Souza, PBT(ASCP), BS Cherise Ens, MSc., MLT Valerie Joyner, MBA, MLT(ASCP) Charles E. Walker, MLT(ASCP)
Supporting Resources
CLSI PRE02QG
Collection of Diagnostic Venous Blood Specimens Quick Guide, 8th Edition
Companion
Preexamination Processes
Free