Resources

This toolkit is designed to support laboratories through the performance of a verification or validation study to update breakpoints. 

ECOFF Finder is designed to estimate epidemiological cutoff values (ECVs, ECOFFs) for the minimal inhibitory concentrations or minimal effective concentrations of wild-type bacterial or fungal populations. 

RangeFinder MIC and RangeFinder Disk are Microsoft Excel spreadsheet calculators that assist with estimating quality control ranges for studies that follow the CLSI M23 standard.

CLSI’s MicroFree™ platform enables users to freely access important information on Antimicrobial Susceptibility Testing, a critical need for laboratories and providers dealing with drug-resistant pathogens and infections.

Find and download meeting minutes and materials from CLSI AST Subcommittees sessions. 

This AST newsletter, authored by the CLSI AST Working Group on Outreach, provides information about current AST practices, recommendations, and resources for the clinical microbiology community.

Rationale documents describe the scientific reasons behind CLSI standards and guidance including the standardized data and methods used to determine breakpoints and interpretive categories.

ASM, in collaboration with CLSI and CAP, has developed ICQP templates for Quality Control of commercial cartridge-based molecular test systems, clinical microbiology tests, and AST.

This template describes how to organize IQCP for disk diffusion susceptibility testing. This is based in part on information included in CLSI EP23 Laboratory Quality Control Based on Risk Management and CDC/CMS “Developing an IQCP, A Step-by-Step Guide.” 

This overview of the AST Subcommittees and meeting protocols is designed for the participant attending AST working meetings for the first time. 

A reference of breakpoints eliminated from CLSI document CLSI M100 Since 2010.

Description of methods no longer considered reliable for testing, including Modified Hodge Test and tests for detecting methicillin (oxacillin) resistance.

QC Ranges eliminated from CLSI document CLSI M100 Since 2010.

Epidemiological Cutoff Values (ECVs) eliminated from CLSI document CLSI M100 Since 2010.

Quickly reference the most trusted AST veterinary breakpoint tables as a convenient, complimentary supplement to the AST VET01 document.