Become a CLSI member to access standards implementation tools and resources.
Resources
At CLSI, we are dedicated to providing laboratories with the essential tools and resources to maintain the highest standards of quality and accuracy.
Discover a wealth of essential tools and resources, from analytic tools to implementation kits and protocols to enhance laboratory testing accuracy and efficiency.

Elevate Your Lab’s Performance @Model.HeadlineType>
Ensure Readiness with these Important Resources @Model.HeadlineType>
CLSI is committed to providing access to tools, news, and updates related to antimicrobial resistance (AMR) and antimicrobial susceptibility testing (AST).
This toolkit is designed to support laboratories through the performance of a verification or validation study to update breakpoints.
ECOFF Finder is designed to estimate epidemiological cutoff values (ECVs, ECOFFs) for the minimal inhibitory concentrations or minimal effective concentrations of wild-type bacterial or fungal populations.
RangeFinder MIC and RangeFinder Disk are Microsoft Excel spreadsheet calculators that assist with estimating quality control ranges for studies that follow the CLSI M23 standard.
CLSI’s MicroFree™ platform enables users to freely access important information on Antimicrobial Susceptibility Testing, a critical need for laboratories and providers dealing with drug-resistant pathogens and infections.
Find and download meeting minutes and materials from CLSI AST Subcommittees sessions.
This AST newsletter, authored by the CLSI AST Working Group on Outreach, provides information about current AST practices, recommendations, and resources for the clinical microbiology community.
Rationale documents describe the scientific reasons behind CLSI standards and guidance including the standardized data and methods used to determine breakpoints and interpretive categories.
ASM, in collaboration with CLSI and CAP, has developed ICQP templates for Quality Control of commercial cartridge-based molecular test systems, clinical microbiology tests, and AST.
This template describes how to organize IQCP for disk diffusion susceptibility testing. This is based in part on information included in CLSI EP23 Laboratory Quality Control Based on Risk Management and CDC/CMS “Developing an IQCP, A Step-by-Step Guide.”
This overview of the AST Subcommittees and meeting protocols is designed for the participant attending AST working meetings for the first time.
A reference of breakpoints eliminated from CLSI document CLSI M100 Since 2010.
Description of methods no longer considered reliable for testing, including Modified Hodge Test and tests for detecting methicillin (oxacillin) resistance.
QC Ranges eliminated from CLSI document CLSI M100 Since 2010.
Epidemiological Cutoff Values (ECVs) eliminated from CLSI document CLSI M100 Since 2010.
Webinars and Education Programs
CLSI offers a range of webinars, self-directed eLearning courses and educational programs to promote the interpretation and implementation of standards and quality management practices.
Harmonized Terminology Database
The Harmonized Terminology Database (HTD) is a compilation of internationally accepted terminology to assist members of the laboratory sciences and related health care industries and promote the use of standardized language and terminology.
Standards Development Policies and Processes
This document contains the approved policies and processes for developing CLSI consensus standards and guidelines, supplements, and derivative products.
Sign Up for our Newsletter
You'll receive the latest updates on new standards, guidelines, and educational resources, as well as expert insights to help enhance your laboratory's performance and compliance.
Hear from Our Members and Partners @Model.HeadlineType>
Our case studies offer practical examples of how labs, health systems, clinics, and countries have successfully implemented guidelines, overcome challenges, and achieved improvements in testing accuracy and efficiency.
Geisinger Expands Access with CLSI Membership
Geisinger utilized CLSI’s Health System Membership to streamline access to vital laboratory standards across their entire health network. This approach has helped enhance operational efficiency and improve patient outcomes by ensuring all labs adhere to the same high-quality standards.