Join us in celebrating our 50th anniversary.
Join us in celebrating our 50th anniversary.

A History of CLSI's Work on Antimicrobial Susceptibility Testing

Through successful standards projects, CLSI (formerly NCCLS) was able to document and advance state of the art processes and procedures in the field of laboratory medicine. Through the cooperation of clinical microbiologists, laboratory industry professionalsand regulators, CLSI standards for antimicrobial susceptibility testing (AST) became a model for improving laboratory practice through voluntary consensus.

In December of 1986 NCCLS published the first edition of M100—Performance Standards for Antimicrobial Susceptibility Testing. M100 provides up-to-date AST breakpoints to laboratory professionals. This information helps health care providers treat their patients with the most effective antimicrobial drugs, as well as helping to slow antimicrobial resistance (AMR). AMR is currently one of the top global health threats. CLSI continues to publish M100 annually.

Scroll down or click the year to the left to learn more about the history of AST at CLSI.

1975

1981

1982

1983

1984

1985

1986

1987

1988

1989

1991