Global Standards for Antimicrobial Susceptibility Testing
Maximize Your Lab’s Effectiveness With the Latest Editions of CLSI M02, M07 & M100
Make sure your lab has the latest guidance in antimicrobial susceptibility testing, breakpoints, and quality control! Use of these newly updated standards and breakpoints is critical to ensuring accurate testing results and better patient outcomes. Purchase all three documents together to receive discounted package pricing! See below for more information.
CLSI M100 - 2025 Preorder
Performance Standards for Antimicrobial Susceptibility Testing, 35th Edition
CLSI M100-Ed35 includes updated tables for the Clinical and Laboratory Standards Institute antimicrobial susceptibility testing standards CLSI M02| Performance Standards for Antimicrobial Disk Susceptibility Tests, 14th Edition (2024), CLSI M07| Methods for Dilution Antimicrobial Susceptibility Tests for Bacteria That Grow Aerobically, 12th Edition (2024), and CLSI M11 | Methods for Antimicrobial Susceptibility Testing of Anaerobic Bacteria, 9th Edition (2018).
CLSI M02
Performance Standards for Antimicrobial Disk Susceptibility Tests, 14th Edition
CLSI M02 covers the current recommended methods for disk susceptibility testing and criteria for quality control testing.
CLSI M07
Methods for Dilution Antimicrobial Susceptibility Tests for Bacteria That Grow Aerobically, 12th Edition
CLSI M07 covers reference methods for determining minimal inhibitory concentrations of aerobic bacteria by broth macrodilution, broth microdilution, and agar dilution.
Register Now for the AST Updates Webinar on 26 February 2025!
Identify the major changes found in the updated edition of CLSI’s M100 and learn to design a strategy for implementing new laboratory practices.
CLSI 2025 M100 Update Webinar
Implement CLSI M100 With Confidence
Date: Wednesday, 26 February at 1:00-2:30 ET
Moderator:
Janet Hindler, MCLS, MT(ASCP), F(AAM)
Speakers:
April Bobenchik, PhD, D(ABMM)
Romney Humphries, PhD D(ABMM)
Join CLSI on Wednesday, 26 February at 1:00 ET for a webinar on the latest in Antimicrobial Susceptibility Testing (AST) with the release of CLSI M100 Ed35. Receive the latest guidance for implementing new breakpoints and standards into your laboratory practices, including discussion of the major changes in this edition, including:
- A significant addition of a new appendix
- Expanded QC guidance
- Removal of breakpoint
- A new categorization of disk diffusion methods described in CLSI M02.
Featured CLSI Products | Access Breakpoint Implementation Guidance
CLSI Breakpoint Implementation Toolkit
Breakpoint Implementation Toolkit
Together CLSI, Association of Public Health Laboratories (APHL), American Society for Microbiology (ASM), College of American Pathologists (CAP), and Centers for Disease Control and Prevention (CDC), have jointly developed this Breakpoint Implementation Toolkit (BIT) to assist clinical laboratories in updating minimal inhibitory concentration (MIC) breakpoints.
CLSI BIT Webinar
Get Current! Using the 2023 Breakpoint Implementation Toolkit to Update and Document AST Breakpoints
Clinical and Laboratory Standards Institute (CLSI), Association of Public Health Laboratories (APHL), American Society for Microbiology (ASM), College of American Pathologists (CAP), and Centers for Disease Control and Prevention (CDC), have jointly developed this Breakpoint Implementation Toolkit (BIT) to assist clinical laboratories in updating minimal inhibitory concentration (MIC) breakpoints.
Other Ways to Access CLSI M100 Ed35
eCLIPSE
Access CLSI's full library of standards—including CLSI M100—with eCLIPSE Ultimate Access, an enhanced, premium platform with advanced features to help you access standards quickly and easily. Included in some membership levels or purchased separately.
M100 Plus
Get full online access to M100, M02, M07, and M11 with added functionality and fast, easy data searching in an electronic format. Plus, you’ll have the added benefit of quick access to related materials via an AST Resource Center.
MicroFree
With this read-only web version of M100, you can now quickly reference the most trusted AST breakpoints from anywhere with an Internet connection. Available online as a convenient companion to our M100 document.
2025 AST Packages | Bundle these latest editions and receive them at a discounted rate.
With important updates for all three documents, CLSI is offering discount package pricing for those that choose to bundle and save.
CLSI CLSI M02 + M100 Print
CLSI M02 + M100 Print
CLSI M02 + M100 - Print
CLSI CLSI M02 + M100 PDF
CLSI M02 + M100 PDF
CLSI M02 + M100 PDF
CLSI CLSI M07 + M100 Print
CLSI M07 + M100 Print
CLSI M07 + M100 Print
CLSI CLSI M07 + M100 PDF
CLSI M07 + M100 PDF
CLSI M07 + M100 PDF
CLSI CLSI M02 + M07+ M100 Print
CLSI M02 + M07+ M100 Print
CLSI M02 + M07+ M100 Print
CLSI CLSI M02 + M07+ M100 PDF
CLSI M02 + M07+ M100 PDF
CLSI M02 + M07+ M100 PDF
Save With a CLSI Membership
Consider becoming a CLSI member to save up to 70% on documents and educational products and gain access to the most up-to-date standards via eCLIPSE, our full online library.
